IPE: Estimating the ImmunoPrecipitation (IP) efficiency of a ChIP-seq experiment.
Description
Calculate the IP efficiency of an experiment by using the mixture model parameters.
Usage
IPE(para, method = NULL)
Arguments
para
A numeric vector. The parameters estimated by the mixture model.
method
A charater variable. Can be "poisson" or "NB" and it refers to the densities of the mixture distribution.
Value
IPE estimated value.
References
Bao et al. Accounting for immunoprecipitation efficiencies in the statistical analysis of ChIP-seq data. BMC Bioinformatics 2013, 14:169 DOI:10.1186/1471-2105-14-169.