fcros (version 1.6-6)

scoreThr: Determine numerically a threshold for the ranking score

Description

Given a log 10 transformed of the sorted ranking score values (dscore), this function determines numerically a threshold (inflection point) for significance of sequencing value level. User should specify the lower and the upper bounds of the slope region containing the inflection point.

Usage

scoreThr(dscore, deb, fin)

Value

This function returns two values: ``pos'' and ``thr'' which are the index or the number of genes with significant values and the score (-log10(score)) threshold

Arguments

dscore

transformed score values obtained using the function rankReads()

deb

integer for lower bound of the slope region containing the inflection point. User should perfom a plot to determine this value

fin

integer for upper bound of the slope region containing the inflection point. User should perfom a plot to determine this value

Author

Doulaye Dembele [e-mail]

References

Dembele D, Analysis of high-throughput biological data using their rank values, Stat Meth Med Res, 2019, 28(8)2276-2291

Examples

#    data(fdata);