getRandomEnrichment: get enrichment based on randomized feature overlap
Description
This function measures the association between two genomic features by randomizing one feature and counting the overlaps in randomized sets.
That is to say, query feature will be randomly distributed over the genome (constrained by provided options), and the overlap of target with these randomized features will be measured.
## S3 method for class 'GRanges,GRanges':
getRandomEnrichment(target, query,
randomizations = 1000, rand.set = NULL, ...)
Arguments
target
a GRanges object to be overlapped with query
query
a GRanges object that will be randomly placed across the genome and overlap of these random regions with target will be the background distribution of association between target and query.
randomizations
number of times the features to be shuffled
rand.set
instead of randomly placing features in query one can supply an already shuffled set of query genomic features.
...
other parameters to be passed to randomizeFeature function. These parameters ccontrol how randomization is done.