groupedSurv (version 1.0.5.1)

PvalueFam: Estimate P-values of the Efficient Score Statistics for the Frailty Model

Description

A method to estimate the p-value for the efficient score statistics for the frailty model.

Usage

PvalueFam(U)

Value

A data.frame with one row for each variables of interest and four columns: stat, the efficient score statistic, pvalue, unadjusted p-value, FWER, the family-wise error rate adjusted p-value (Bonferroni correction), and FDR, the local false-discovery rate (Storey's Q-value).

Arguments

U

Matrix of contributions of each family to the efficient score statistics of each variable of interest, (i.e., the output from groupedSurvFam).

References

Bonferroni, C.E. (1935). Il calcolo delle assicurazioni su gruppi di teste. Studi in Onore del Professore Salvatore Ortu Carbon, 13-60.
Storey, J.D. (2003). The positive false discovery rate: a Bayesian interpretation and the q-value. Annals of Statistics, 31:6, 2013-2035.
Storey, J.D., Taylor, J.E., and Siegmund, D. (2004). Strong control, conservative point estimation and simultaneous conservative consistency of false discovery rates: a unified approach. Journal of the Royal Statistical Society Series B-Statistical Methodology, 66, 187-205

Examples

# Generate dummy data	
U <- matrix(rnorm(10000), ncol=50)

#res   <- PvalueFam(U) 
#res