CleanAllele

This function takes raw messy HLA(Human Leukocyte Antigen) typing data as input. It removes inconsistent formatting and unnecessary symbols. If one of two alleles at a loci is NA, the locus is assumed to be homozygous.

A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

Joan Zhang

hlaR

Tools for HLA Data

Aileen Johnson

Christian P Larsen

CleanAllele function

<dl><dt>var_1</dt>
<dd>HLA on allele 1.</dd>
<dt>var_2</dt>
<dd>HLA on allele 2.</dd></dl>

Arguments

Clean messy HLA typing data — CleanAllele

<dl>

<dt>var_1</dt>
<dd>HLA on allele 1.</dd>


<dt>var_2</dt>
<dd>HLA on allele 2.</dd>

</dl>

CleanAllele: Clean messy HLA typing data

Description

Usage

Value

Arguments

Examples