CountAlleleMism

Donor and recipient HLA(Human Leukocyte Antigen) typing data is compared to determine allele level mismatch. The output of EvalAlleleMism is used as input for this function. Allele level mismatch can be calculated for both high and low resolution data. The generated count will return NA if the input alleles are NA.

A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

Joan Zhang

hlaR

Tools for HLA Data

Aileen Johnson

Christian P Larsen

CountAlleleMism function

<dl><dt>dat_in</dt>
<dd>A data frame with donor and recipient mismatched alleles. It's a output from EvalAlleleMism function.</dd>
<dt>names_in</dt>
<dd>A vector of HLA loci name to count mismatch for.</dd></dl>

Arguments

Count HLA mismatch at the allele level — CountAlleleMism

<dl>

<dt>dat_in</dt>
<dd>A data frame with donor and recipient mismatched alleles. It's a output from EvalAlleleMism function.</dd>


<dt>names_in</dt>
<dd>A vector of HLA loci name to count mismatch for.</dd>

</dl>

CountAlleleMism: Count HLA mismatch at the allele level

Description

Usage

Value

Arguments

Examples