isr.volume

Calculates the estimated serum volume (mL) based on patient sex, weight, and
height for use in <code>isr.deconv()</code>.

Calculates insulin secretion rates from C-peptide values
based on the methods described in Van Cauter et al. (1992)
<doi:10.2337/diab.41.3.368>. Includes functions to calculate estimated
insulin secretion rates using linear or cubic spline interpolation of
c-peptide values (see Eaton et al., 1980 <doi:10.1210/jcem-51-3-520>
and Polonsky et al., 1986 <doi:10.1172/JCI112308>) and to calculate
estimates of input coefficients (volume of distribution, short half life,
long half life, and fraction attributed to short half life) as described by
Van Cauter. Although the generated coefficients are specific to insulin
secretion, the two-compartment secretion model used here is useful for
certain applications beyond insulin.

Ken Stier

insulin.secretion

Insulin Secretion Rate Deconvolution

isr.volume function

<dl><dt>subject.sex</dt>
<dd>String for patient sex, <code>"m"</code> or <code>"f"</code>.</dd>
<dt>subject.weight</dt>
<dd>Numeric for subject weight in kilograms.</dd>
<dt>subject.height</dt>
<dd>Numeric for subject height in centimeters.</dd></dl>

Arguments

Serum Volume Calculator — isr.volume

<dl>

<dt>subject.sex</dt>
<dd>String for patient sex, <code>"m"</code> or <code>"f"</code>.</dd>


<dt>subject.weight</dt>
<dd>Numeric for subject weight in kilograms.</dd>


<dt>subject.height</dt>
<dd>Numeric for subject height in centimeters.</dd>

</dl>

isr.volume: Serum Volume Calculator

Description

Usage

Value

Arguments

See Also

Examples