Matrix of effect sizes. Each column of ES corresponds to one study and each row to one gene.
varES
Matrix of effect size variances. Each column of varES corresponds to one study and each row to one gene.
BHth
Benjamini Hochberg threshold. By default, the False Discovery Rate is controlled at 5%.
useREM
A logical value indicating whether or not to include the between-study variance into the model.
Value
List
DEindicesIndices of differentially expressed genes at the chosen Benjamini Hochberg threshold.
TestStatisticVector with test statistics for differential expression in the meta-analysis.
Details
Combines effect sizes with the method presented in (Choi et al., 2003).
References
Choi, J. K., Yu, U., Kim, S., and Yoo, O. J. (2003). Combining multiple microarray
studies and modeling interstudy variation. Bioinformatics, 19 Suppl 1.