nlmixr_fit

Parsed nlmixr model (by <code>nlmixr(mod.fn)</code>).

Dataset to estimate. Needs to be RxODE compatible in
EVIDs.

data

Estimation control options. They could be
<code><a rd-options="nlme" href="/link/nlmeControl?package=nlmixr&version=0.9.1-2&to=nlme" data-mini-rdoc="nlme::nlmeControl">nlmeControl</a></code>, <code><a rd-options="" href="/link/saemControl?package=nlmixr&version=0.9.1-2" data-mini-rdoc="nlmixr::saemControl">saemControl</a></code>

control

Parameters passed to estimation method.

Take the RxODE model and use more precise
products/sums. Increases solving accuracy and solving time.

sum.prod

Translate the model to FOCEi and then run
the tables and objective function so that different estimation
methodologies are comparable through OBJF.

calc.resid

Fit and compare nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'RxODE' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Wenping Wang

nlmixr

Nonlinear Mixed Effects Models in Population Pharmacokinetics
and Pharmacodynamics

Matthew Fidler

Yuan Xiong

Rik Schoemaker

Justin Wilkins

Mirjam Trame

Teun Post

Robert Leary

Hadley Wickham

Dirk Eddelbuettel

David Ardia

Katharine Mullen

nlmixr_fit function

Estimation control options. They could be
<code><a rd-options='nlme' href='nlmeControl'>nlmeControl</a></code>, <code><a rd-options='' href='saemControl'>saemControl</a></code>

nlmixr_fit: Fit a nlmixr model

Description

Usage

Arguments

Value