rxHessian

<p>Get the Hessian for the environment</p>

internal

Fit and compare nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'RxODE' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Wenping Wang

nlmixr

Nonlinear Mixed Effects Models in Population Pharmacokinetics
and Pharmacodynamics

Matthew Fidler

Yuan Xiong

Rik Schoemaker

Justin Wilkins

Mirjam Trame

Teun Post

Robert Leary

Hadley Wickham

Dirk Eddelbuettel

David Ardia

Katharine Mullen

rxHessian function

Get the Hessian for the environment — rxHessian

Get the Hessian for the environment

rxHessian: Get the Hessian for the environment

Description

Usage

Arguments