Cox Box transformation
Construct RxODE linCmt function
Return composite nlme/focei to nlme
Add CWRES
instant.stan.extension.
Inverse Guassian absorption model
nlmixr fits population PK and PKPD non-linear mixed effects models.
Augmented Prediction for nlmixr fit
Get parameters that are fixed
Get the FOCEi initializations
Get initial estimate for ares SAEM.
NPDE calculation for nlmixr
Get initial estimate for bres SAEM.
Generate SAEM initial estimates for THETA.
Get model$log.eta for SAEM
Validate nlmixr
Dispaly nlmixr's version
Plot an SAEM model fit
Prediction after a gnlmm fit
Covariance matrix by Fisher Information Matrix via linearization
Pregnant Rat Diet Experiment
Calculate gnlmm variance-covariance matrix of fixed effects
This gets the parsed data in the lower-level manner that nlmixr expects.
Fit a non-population dynamic model
Objects exported from other packages
concentrations from a linear compartment model
Parameters for a linear compartment model for SAEM
GOF plots for nlme-based mixed-effect models
Access the model list information for nlmixr's nlme user functions
Bolus_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
nlmixrBounds.focei.upper.lower
Get upper/lower/names for THETAs
Generalized Cholesky Matrix Decomposition
1 Compartment Model w/ Michelis Menton Elimination
Convert/Format the data appropriately for nlmixr
Return VarCorr for nlmixr nlme
2 Compartment Model
Configure an SAEM model
Generate saem.fit user function.
2 Compartment Model with Michelis Menton Clearance
Simulated Data Set for comparing objective functions
Bootstrap data
FOCEi fit
Fit a generalized nonlinear mixed-effect model
Return composite saem/focei to saem
Fit/Evaulate FOCEi
Get parameters that are fixed for SAEM
Log-likelihood using Gaussian Quadrature
Change a nlmixr fit object to a huxtable
Get the FOCEi theta specification for the model
Visual predictive check (VPC) for nlmixr nlme objects
nlmixr ini block handling
Fit a non-population dynamic model using mcmc
Get the FOCEi theta or eta specification for model.
VPC for nlmixr saemFit objects
Get THETA names for nlmixr's SAEM
Control Options for FOCEi
Parent/Metabolite dataset
Forward covariate selection for nlme-base non-linear mixed effect models
Generate an SAEM model
Calculate gnlmm variance-covariance matrix of random effects
Extract the Nlmixr bound information from a function.
Get the Parameter function with THETA/ETAs defined
Sets nodes and weigts of Gauss-Hermite quadrature
VPC based on ui model
Fit nlme-based linear compartment mixed-effect model using closed form solution
Warfarin PK/PD data
Fit nlme-based mixed-effect model using ODE implementation
Get ETA names
Predict a nlmixr solved system
nlmixr model block
Fit a nlmixr model
Simulate a nlmixr solved system
Find the assignments in R expression
Print x using the message facility
Prepares the UI function and returns a list.
Print a gnlmm fit
nlmixrUI.saem.distribution
Get SAEM distribution
Clear memoise cache for nlmixr
Get the eta->eta.trans for SAEM
Messages the nlmixr logo...
Create the nlme specs list for nlmixr nlme solving
Generate SAEM model list
Get the variance for the nlme fit process based on UI
Print UI function
nlmixrUI.saem.model.omega
Get the SAEM model Omega
Create a large output based on a nlmixr fit
Nelder-Mead of simplex search
Plot of a non-population dynamic model fit using mcmc
Get saem initilization list
Extract residuals from the FOCEI fit
Create the nlme parameter transform function from the UI object.
Cleanup saem_fit environment by removing dll after the object is no logner used by R.
Return RxODE model with predictions appended
Plot a nlmixr data object
Get the SAEM model$res.mod code
Multiple dose Theophiline PK data
Set Objective function type for a nlmixr object
Multiple dose Theophiline PK data
Get error names for SAEM
Convert data to RxODE format (depreciated)
Return the square root of general square matrix A
SAEM's init$omega
Summary of a non-population dynamic model fit
Create a run summary word document
Get a list of directories for inclusion
Summary of a non-population dynamic model fit using mcmc
Return the objective function
Print a non-population dynamic model fit object
Summary of a non-population dynamic model fit using mcmc
Single Dose Phenobarbitol PK/PD
Plot of a non-population dynamic model fit
Print an SAEM model fit summary
Produce trace-plot for fit if applicable
Pump failure example dataset
Vpc function for nlmixr
Yeo-Johnson Transformation
Fit an SAEM model
Control Options for SAEM
Print an SAEM model fit summary
Output table/data.frame options
Oral_1CPT -- 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
Infusion_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
Convert fit to FOCEi style fit