pump

Thir records the number of failures and operation time for groups
of 10 pumps.

datasets

Fit and compare nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'RxODE' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Wenping Wang

nlmixr

Nonlinear Mixed Effects Models in Population Pharmacokinetics
and Pharmacodynamics

Matthew Fidler

Yuan Xiong

Rik Schoemaker

Justin Wilkins

Mirjam Trame

Richard Hooijmaijers

Teun Post

Robert Leary

Hadley Wickham

Dirk Eddelbuettel

Johannes Pfeifer

Robert B. Schnabel

Elizabeth Eskow

Emmanuelle Comets

Audrey Lavenu

Marc Lavielle

David Ardia

Bill Denney

Katharine Mullen

pump function

A data frame with 10 rows and 5 columns<dl class="dl-horizontal">
 <dt>y</dt><dd>Number of pump failures</dd>
 <dt>t</dt><dd>Failure Time</dd>
 <dt>group</dt><dd>Continuous Operation (=1) or Intermittent Operation(=2)</dd>
 <dt>ID</dt><dd>ID for group of 10 pumps</dd>
 <dt>logtstd</dt><dd>Centeredy operation times</dd>
</dl>

Format

Pump failure example dataset — pump

A data frame with 10 rows and 5 columns<dl class='dl-horizontal'>
 <dt>y</dt><dd>Number of pump failures</dd>
 <dt>t</dt><dd>Failure Time</dd>
 <dt>group</dt><dd>Continuous Operation (=1) or Intermittent Operation(=2)</dd>
 <dt>ID</dt><dd>ID for group of 10 pumps</dd>
 <dt>logtstd</dt><dd>Centeredy operation times</dd>
</dl>

Pump failure example dataset

pump: Pump failure example dataset

Description

Usage

Arguments

Format

References