NPDE calculation for nlmixr
addNpde(
object,
nsim = 300,
ties = TRUE,
seed = 1009,
updateObject = TRUE,
cholSEtol = (.Machine$double.eps)^(1/3),
...
)
nlmixr fit object
Number of simulations. By default this is 300
When TRUE, the npde distribution can have ties. When FALSE, the npde distribution uses uniform random numbers to prevent ties.
Seed for running nlmixr simulation. By default 1009
Boolean indicating if original object should be updated. By default this is TRUE.
tolerance for Generalized Cholesky Decomposition. Defaults to suggested (.Machine$double.eps)^(1/3)
Other ignored parameters.
New nlmixr fit object