Return VarCorr for nlmixr nlme
Infusion_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
2 Compartment Model
NPDE calculation for nlmixr
Cox Box, Yeo Johnson and inverse transformation
Covariance matrix by Fisher Information Matrix via linearization
Return composite saem/focei to saem
Bolus_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
Bootstrap data
Convert fit to FOCEi style fit
Return composite nlme/focei to nlme
Fit a non-population dynamic model using mcmc
2 Compartment Model with Michelis Menton Clearance
Get the FOCEi theta or eta specification for model.
Calculate gnlmm variance-covariance matrix of fixed effects
Log-likelihood using Gaussian Quadrature
Construct RxODE linCmt function
Calculate gnlmm variance-covariance matrix of random effects
Generate an SAEM model
Control Options for FOCEi
Get the FOCEi theta specification for the model
Parameters for a linear compartment model for SAEM
concentrations from a linear compartment model
This gets the parsed data in the lower-level manner that nlmixr expects.
Fit nlme-based mixed-effect model using ODE implementation
GOF plots for nlme-based mixed-effect models
Fit nlme-based linear compartment mixed-effect model using closed form solution
Fit a non-population dynamic model
Access the model list information for nlmixr's nlme user functions
instant.stan.extension.
SAEM dll prodection from garbage collection
Create a gradient function based on gill numerical differences
Calculate Hessian
Generate saem.fit user function.
Create the nlme parameter transform function from the UI object.
Inverse Guassian absorption model
Return RxODE model with predictions appended
Simulate a nlmixr solved system
nlmixrBounds.focei.upper.lower
Get upper/lower/names for THETAs
Get initial estimate for ares SAEM.
Print x using the message facility
Get parameters that are fixed for SAEM
Create a large output based on a nlmixr fit
Nelder-Mead of simplex search
Create a run summary word document
Forward covariate selection for nlme-base non-linear mixed effect models
Sets nodes and weigts of Gauss-Hermite quadrature
Convert data to RxODE format (depreciated)
Print an SAEM model fit summary
Get ETA names
Convert/Format the data appropriately for nlmixr
Extract the Nlmixr bound information from a function.
Print an SAEM model fit summary
Output table/data.frame options
Get parameters that are fixed
Get the FOCEi initializations
Generalized Cholesky Matrix Decomposition
Pump failure example dataset
Produce trace-plot for fit if applicable
Fit a nlmixr model
Get saem initilization list
Plot an SAEM model fit
SAEM's init$omega
Prediction after a gnlmm fit
Extract residuals from the FOCEI fit
Validate nlmixr
Parent/Metabolite dataset
Get initial estimate for bres SAEM.
Dispaly nlmixr's version
nlmixrUI.saem.model.omega
Get the SAEM model Omega
Generate SAEM model list
Configure an SAEM model
nlmixr model block
Get the optimal forward difference interval by Gill83 method
Clear memoise cache for nlmixr
Vpc function for nlmixr
Return the objective function
Find the assignments in R expression
Print a non-population dynamic model fit object
Summary of a non-population dynamic model fit using mcmc
Create the nlme specs list for nlmixr nlme solving
Generate SAEM initial estimates for THETA.
Get the variance for the nlme fit process based on UI
Get a list of directories for inclusion
Cleanup saem_fit environment by removing dll after the object is no logner used by R.
Get model$log.eta for SAEM
Get the SAEM model$res.mod code
FOCEi fit
Single Dose Phenobarbitol PK/PD
Fit/Evaulate FOCEi
Get error names for SAEM
Set Objective function type for a nlmixr object
Objects exported from other packages
Visual predictive check (VPC) for nlmixr nlme objects
Return the square root of general square matrix A
Fit a generalized nonlinear mixed-effect model
nlmixr ini block handling
Plot of a non-population dynamic model fit
Summary of a non-population dynamic model fit
VPC for nlmixr saemFit objects
Pregnant Rat Diet Experiment
Summary of a non-population dynamic model fit using mcmc
VPC based on ui model
Multiple dose Theophilline PK data
Multiple dose Theophilline PK data
nlmixr fits population PK and PKPD non-linear mixed effects models.
Augmented Prediction for nlmixr fit
Messages the nlmixr logo...
Predict a nlmixr solved system
Warfarin PK/PD data
Prepares the UI function and returns a list.
nlmixrUI.saem.distribution
Get SAEM distribution
Get the eta->eta.trans for SAEM
Return dynmodel variable translation function
Get THETA names for nlmixr's SAEM
Plot of a non-population dynamic model fit using mcmc
Print a gnlmm fit
Get the Parameter function with THETA/ETAs defined
Plot a nlmixr data object
Print UI function
Control Options for SAEM
Fit an SAEM model
Add CWRES
Simulated Data Set for comparing objective functions
Oral_1CPT -- 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
1 Compartment Model w/ Michelis Menton Elimination