nlmixr2auto (version 1.0.0)

spaceConfig: Get search space configuration

Description

Retrieve the configuration for a specified search space.

Usage

spaceConfig(search.space = c("ivbase", "oralbase"))

Value

A list with four elements:

• route: Administration route ("bolus", "oral", or NULL).

• params: Character vector of parameter names expected in the string vector.

• param_dependencies: Named list of functions that compute dependent parameters.

• fixed_params: Named list of fixed parameter values.

Arguments

search.space

Character, one of "ivbase" or "oralbase". Default is "ivbase".

Author

Zhonghui Huang

Details

Pre-defined search spaces:

• "ivbase": IV bolus model, 11 parameters, supports 1 to 3 compartments.

• "oralbase": Oral model, 12 parameters (adds eta.ka), supports 1 to 3 compartments.

For "ivbase" and "oralbase", param_dependencies handle the relationship between Michaelis-Menten elimination (mm) and the associated variability parameters (eta.vmax, eta.cl).

See Also

mod.run for the main function that uses these configurations. parseParams for parameter parsing using configurations.

Examples

# Get IV base configuration
config <- spaceConfig("ivbase")
config$params

# Get oral base configuration
config <- spaceConfig("oralbase")
config$params