mavoglurant

This was used in a full PBPK model. This one was published for mavoglurant
(Wendling et al. 2016).

datasets

Datasets for 'nlmixr2' and 'rxode2'. 'nlmixr2' is used for fitting and comparing
nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'rxode2' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Matthew Fidler

nlmixr2data

Nonlinear Mixed Effects Models in Population PK/PD, Data

Rik Schoemaker

Kyle Baron

Thierry Wendling

Ted Grasella

C Weil

Yaning Wang

R O'Reilly

David D'Argenio

 Rodriguez-Vera

D Gaver

Yuan Xiong

Wenping Wang

mavoglurant function

A data frame with 2,678 rows by 14 columns<dl>
<dt>ID</dt>
<dd>Subject ID</dd><dt>CMT</dt>
<dd>Compartment Number</dd><dt>EVID</dt>
<dd>Event ID</dd><dt>MDV</dt>
<dd>Missing DV</dd><dt>DV</dt>
<dd>Dependent Variable, Mavoglurant</dd><dt>AMT</dt>
<dd>Dose Amount Keyword</dd><dt>TIME</dt>
<dd>Time (hr)</dd><dt>DOSE</dt>
<dd>Dose</dd><dt>OCC</dt>
<dd>Occasion</dd><dt>RATE</dt>
<dd>Rate</dd><dt>AGE</dt>
<dd>Age</dd><dt>SEX</dt>
<dd>Sex</dd><dt>WT</dt>
<dd>Weight</dd><dt>HT</dt>
<dd>Height</dd>
</dl>

Format

Mavoglurant PK data — mavoglurant

A data frame with 2,678 rows by 14 columns<dl>
<dt>ID</dt>
<dd>Subject ID</dd>

<dt>CMT</dt>
<dd>Compartment Number</dd>

<dt>EVID</dt>
<dd>Event ID</dd>

<dt>MDV</dt>
<dd>Missing DV</dd>

<dt>DV</dt>
<dd>Dependent Variable, Mavoglurant</dd>

<dt>AMT</dt>
<dd>Dose Amount Keyword</dd>

<dt>TIME</dt>
<dd>Time (hr)</dd>

<dt>DOSE</dt>
<dd>Dose</dd>

<dt>OCC</dt>
<dd>Occasion</dd>

<dt>RATE</dt>
<dd>Rate</dd>

<dt>AGE</dt>
<dd>Age</dd>

<dt>SEX</dt>
<dd>Sex</dd>

<dt>WT</dt>
<dd>Weight</dd>

<dt>HT</dt>
<dd>Height</dd>


</dl>

Mavoglurant PK data

mavoglurant: Mavoglurant PK data

Description

Usage

Arguments

Format

See Also