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nlmixr2data

The goal of nlmixr2data is to include all the example datasets from the nlmixr2 project in one place.

Example

This shows the theo_sd dataset, the hello world for nlmixr2.

library(nlmixr2data)
head(theo_sd)
#>   ID TIME    DV     AMT EVID CMT   WT
#> 1  1 0.00  0.00 319.992  101   1 79.6
#> 2  1 0.00  0.74   0.000    0   2 79.6
#> 3  1 0.25  2.84   0.000    0   2 79.6
#> 4  1 0.57  6.57   0.000    0   2 79.6
#> 5  1 1.12 10.50   0.000    0   2 79.6
#> 6  1 2.02  9.66   0.000    0   2 79.6

Installation

You can install the development version of nlmixr2data from GitHub with:

# install.packages("remotes")
remotes::install_github("nlmixr2/nlmixr2data")

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Install

install.packages('nlmixr2data')

Monthly Downloads

1,428

Version

2.0.9

License

GPL (>= 3)

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Maintainer

Matthew Fidler

Last Published

January 31st, 2024

Functions in nlmixr2data (2.0.9)

Oral_2CPTMM

1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
wbcSim

Simulated Friberg Myelosuppression model (Yuan Xiong)
rats

Pregnant Rat Diet Experiment
theo_md

Multiple dose theophylline PK data
theo_sd

Multiple dose theophylline PK data
warfarin

Warfarin PK/PD data
Bolus_1CPTMM

1 Compartment Model w/ Michaelis-Menten Elimination
mavoglurant

Mavoglurant PK data
Oral_2CPT

2 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
Infusion_1CPT

1 Compartment Model Simulated Data from ACOP 2016
Bolus_2CPTMM

2 Compartment Model with Michaelis-Menten Clearance
Infusion_2CPTMM

2 Compartment Model w/MM elimination Simulated Data from ACOP 2016
metabolite

Parent/Metabolite dataset
pump

Pump failure example dataset
Infusion_1CPTMM

1 Compartment Model w/MM elimination Simulated Data from ACOP 2016
Wang2007

Simulated Data Set for comparing objective functions
nmtest

One compartment test dataset showing NONMEM 7.4.3 output
Bolus_1CPT

1 Compartment Model Simulated Data from ACOP 2016
Bolus_2CPT

2 Compartment Model
nimoData

Nimotuzumab PK data
Oral_1CPT

1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
pheno_sd

Single Dose Phenobarbitol PK/PD
Infusion_2CPT

2 Compartment Model with Infusion Simulated Data from ACOP 2016
Oral_1CPTMM

1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
invgaussian

Inverse Guassian absorption model