nmtest

This is a example dataset originally created to show how similar
<code>mrgsolve</code> and NONMEM were (See ).

datasets

Datasets for 'nlmixr2' and 'rxode2'. 'nlmixr2' is used for fitting and comparing
nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'rxode2' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Matthew Fidler

nlmixr2data

Nonlinear Mixed Effects Models in Population PK/PD, Data

Rik Schoemaker

Kyle Baron

Thierry Wendling

Ted Grasella

C Weil

Yaning Wang

R O'Reilly

David D'Argenio

 Rodriguez-Vera

D Gaver

Yuan Xiong

Wenping Wang

nmtest function

A data frame with 7,157 rows and 15 columns
<dl>
<dt>id</dt>
<dd>NONMEM id</dd><dt>time</dt>
<dd>NONMEM time</dd><dt>cp</dt>
<dd>NONMEM cp output from 7.4.3</dd><dt>cmt</dt>
<dd>cmt specification 1=depot, 2=central</dd><dt>amt</dt>
<dd>Nonmem dose</dd><dt>evid</dt>
<dd>NONMEM Event ID</dd><dt>ii</dt>
<dd>Interdose Interval</dd><dt>ss</dt>
<dd>Steady state flag</dd><dt>addl</dt>
<dd>Individual Clearance</dd><dt>rate</dt>
<dd>Rate of the infusion</dd><dt>lagt</dt>
<dd>Lag time</dd><dt>bioav</dt>
<dd>Bioavailability</dd><dt>rat2</dt>
<dd>Modeled rate when <code>mode</code> == 1</dd><dt>dur2</dt>
<dd>Duration when <code>mode</code> == 2</dd><dt>mode</dt>
<dd>Mode = 0 is no modification, modeled rate when mode=1 and modeled duration when mode=2</dd>
</dl>

Format

Author

One compartment test dataset showing NONMEM 7.4.3 output — nmtest

A data frame with 7,157 rows and 15 columns
<dl>
<dt>id</dt>
<dd>NONMEM id</dd>

<dt>time</dt>
<dd>NONMEM time</dd>

<dt>cp</dt>
<dd>NONMEM cp output from 7.4.3</dd>

<dt>cmt</dt>
<dd>cmt specification 1=depot, 2=central</dd>

<dt>amt</dt>
<dd>Nonmem dose</dd>

<dt>evid</dt>
<dd>NONMEM Event ID</dd>

<dt>ii</dt>
<dd>Interdose Interval</dd>

<dt>ss</dt>
<dd>Steady state flag</dd>

<dt>addl</dt>
<dd>Individual Clearance</dd>

<dt>rate</dt>
<dd>Rate of the infusion</dd>

<dt>lagt</dt>
<dd>Lag time</dd>

<dt>bioav</dt>
<dd>Bioavailability</dd>

<dt>rat2</dt>
<dd>Modeled rate when <code>mode</code> == 1</dd>

<dt>dur2</dt>
<dd>Duration when <code>mode</code> == 2</dd>

<dt>mode</dt>
<dd>Mode = 0 is no modification, modeled rate when mode=1 and modeled duration when mode=2</dd>


</dl>

One compartment test dataset showing NONMEM 7.4.3 output

nmtest: One compartment test dataset showing NONMEM 7.4.3 output

Description

Usage

Arguments

Format

Author

Details

See Also