wbcSim

<dl>
<dt>ID</dt>
<dd>Subject ID</dd><dt>TIME</dt>
<dd>Time (hrs)</dd><dt>RATE</dt>
<dd>Rate</dd><dt>AMT</dt>
<dd>Dose Amount Keyword</dd><dt>DV</dt>
<dd>Dependent Variable, WBC</dd><dt>CMT</dt>
<dd>Compartment Number</dd><dt>V2I</dt>
<dd>Input Peripheral Volume</dd><dt>V1I</dt>
<dd>Input Central Volume</dd><dt>V1I</dt>
<dd>Input Clearance</dd><dt>EVID</dt>
<dd>nlmixr2/rxode2 classic evid</dd>
</dl>

datasets

Datasets for 'nlmixr2' and 'rxode2'. 'nlmixr2' is used for fitting and comparing
nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'rxode2' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Matthew Fidler

nlmixr2data

Nonlinear Mixed Effects Models in Population PK/PD, Data

Rik Schoemaker

Kyle Baron

Thierry Wendling

Ted Grasella

C Weil

Yaning Wang

R O'Reilly

David D'Argenio

 Rodriguez-Vera

D Gaver

Yuan Xiong

Wenping Wang

wbcSim function

An object of class <code>data.frame</code> with 280 rows and 10 columns.

Format

<dl>
<dt>ID</dt>
<dd>Subject ID</dd>

<dt>TIME</dt>
<dd>Time (hrs)</dd>

<dt>RATE</dt>
<dd>Rate</dd>

<dt>AMT</dt>
<dd>Dose Amount Keyword</dd>

<dt>DV</dt>
<dd>Dependent Variable, WBC</dd>

<dt>CMT</dt>
<dd>Compartment Number</dd>

<dt>V2I</dt>
<dd>Input Peripheral Volume</dd>

<dt>V1I</dt>
<dd>Input Central Volume</dd>

<dt>V1I</dt>
<dd>Input Clearance</dd>

<dt>EVID</dt>
<dd>nlmixr2/rxode2 classic evid</dd>


</dl>

Simulated Friberg Myelosuppression model (Yuan Xiong) — wbcSim

Simulated Friberg Myelosuppression model (Yuan Xiong)

wbcSim: Simulated Friberg Myelosuppression model (Yuan Xiong)

Description

Usage

Arguments

Format

See Also