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pathifier (version 1.10.0)

Quantify deregulation of pathways in cancer

Description

Pathifier is an algorithm that infers pathway deregulation scores for each tumor sample on the basis of expression data. This score is determined, in a context-specific manner, for every particular dataset and type of cancer that is being investigated. The algorithm transforms gene-level information into pathway-level information, generating a compact and biologically relevant representation of each sample.

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Version

Version

1.10.0

License

Artistic-1.0

Maintainer

Assif Yitzhaky

Last Published

February 15th, 2017

Functions in pathifier (1.10.0)

quantify_pathways_deregulation

Quantify deregulation of pathways in cancer
KEGG

Two pathways of the KEGG database
pathifier-package

Quantify deregulation of pathways in cancer
Sheffer

Sheffer et al. colorectal dataset