Learn R Programming

⚠️There's a newer version (1.2.3) of this package.Take me there.

pksensi (version 1.1.6)

Global Sensitivity Analysis in Physiologically Based Kinetic Modeling

Description

Applying the global sensitivity analysis workflow to investigate the parameter uncertainty and sensitivity in physiologically based kinetic (PK) models, especially the physiologically based pharmacokinetic/toxicokinetic model with multivariate outputs. The package also provides some functions to check the convergence and sensitivity of model parameters.

Copy Link

Version

Install

install.packages('pksensi')

Monthly Downloads

234

Version

1.1.6

License

GPL-3 | file LICENSE

Issues

Pull Requests

Stars

Forks

Maintainer

Nan-Hung Hsieh

Last Published

May 5th, 2020

Functions in pksensi (1.1.6)

about-pksensi

About pksensi package
tell2

The Decoupling Simulations
check

Check the Parameter Sensitivity
mcsim_install

Install GNU MCSim
solve_fun

Solve PK Model Through deSolve Package or Analytical Function
compile_model

Model Compiler
pksim

PK Simulation from Sampling Parameter
APAP

Pharmacokinetic Dataset of Acetaminophen
solve_mcsim

Solve PK Model Through GNU MCSim
rfast99

Extended Fourier Amplitude Sensitivity Test with Random Phase Shift
models

Example PK Model for Sensitivity Analysis