The CombinedWeights object class merges the weight matrices for
all data sets in a plasma object.
data(tfESCA)
data(mirESCA)Both tfData and mirESCA are data frames containng two
columns. The first column is and ID column containing the TCGA
sample barcode for an esophagela cancer sample. The second column,
called Type identifies the sample as either "squamous" (for
likely squamous cell carcinomas that cluster near head and neck
cancers) or "adeno" (for likley adenocarcinomas that cluster near
stomach cancers).
Kevin R. Coombes krc@silicovore.com, Kyoko Yamaguchi kyoko.yamaguchi@osumc.edu
Abrams ZB, Zucker M, Wang M, Asiaee Taheri A, Abruzzo LV, Coombes KR.
Thirty biologically interpretable clusters of transcription
factors distinguish cancer type.
BMC Genomics. 2018 Oct 11;19(1):738. doi: 10.1186/s12864-018-5093-z.
Asiaee A, Abrams ZB, Nakayiza S, Sampath D, Coombes KR.
Explaining Gene Expression Using Twenty-One MicroRNAs.
J Comput Biol. 2020 Jul;27(7):1157-1170. doi: 10.1089/cmb.2019.0321.