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plmDE (version 1.0)

Additive partially linear models for differential gene expression analysis

Description

A set of tools for identifying genes whose differential expression is associated with measurements of other covariates on a continuous scale. These methods rely on generalized additive partially linear models which can be fitted efficiently using a B-spline basis approximation. Still under development: methods for interfacing with objects extending the eSet class and a function to pass linear models in edgeR and DEseq format.

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Version

Install

install.packages('plmDE')

Monthly Downloads

2

Version

1.0

License

GPL (>= 2)

Maintainer

Jonas

Last Published

May 9th, 2012

Functions in plmDE (1.0)

hist.DEresults

Create a Histogram of P-values
plmDEmodel

Constructor for objects of type plmDE
fitBspline

Compute B-Spline Basis for Data
fitGAPLM

Fit a Generalized Additive Partially Linear Model on Gene Expression Data
head.plmDE

Preview of plmDE object
head.DEresults

Preview of Data in DEresults object
limmaPLM

mostDE

Find Genes with the Most Evidence for Differential Expression
info

Information about an Object
plmDE-package

Generalized Additive Partially Linear Models for Gene Expression Data
plot.DEresults

Plot Fit of DEresults Model
plmDEmodel.default

Creates a class to hold Expression Data and Other Measurements
info.plmDE

Obtain Information about plmDE object