Comprehensive Pipeline for Analyzing and Visualizing Array-Based CGH Data
Description
A comprehensive pipeline for analyzing and interactively
visualizing genomic profiles generated through commercial or custom aCGH
arrays. As inputs, rCGH supports Agilent dual-color Feature Extraction
files (.txt), from 44 to 400K, Affymetrix SNP6.0 and cytoScanHD
probeset.txt, cychp.txt, and cnchp.txt files exported from ChAS or
Affymetrix Power Tools. rCGH also supports custom arrays, provided data is
in a suitable format. This package takes over all the steps required for
individual genomic profiles analysis, from reading files to segmenting
and annotating genes. This package provides several visualization functions
(static or interactive) which facilitate individual profiles interpretation.
Input files can be in compressed format, e.g. .bz2 or .gz.