Create a Random List for Crossover Studies
Contains a function to randomize subjects, patients in groups of
sequences (treatment sequences).
If a blocksize is given, the randomization will be done within blocks.
The randomization may be controlled by a Wald-Wolfowitz runs test.
Functions to obtain the p-value of that test are included.
The package is mainly intended for randomization of bioequivalence studies
but may be used also for other clinical crossover studies.
Contains two helper functions sequences() and williams() to get the sequences
of commonly used designs in BE studies.
Functions in randomizeBE
|randomizeBE-package||Create a randomisation list for cross-over studies.|
|williams||Construct sequences of a Williams design|
|runs.pvalue||2-sided p-value of the runs test|
|pruns.exact||Exact cumulative distribution function of runs test|
|RL4||(Block) randomization of subjects, patients into sequence groups|
|print.rl4||S3 method print for class "rl4"|
|sequences||Obtain sequences for BE study designs|
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