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randomizeBE (version 0.3-5)

Create a Random List for Crossover Studies

Description

Contains a function to randomize subjects, patients in groups of sequences (treatment sequences). If a blocksize is given, the randomization will be done within blocks. The randomization may be controlled by a Wald-Wolfowitz runs test. Functions to obtain the p-value of that test are included. The package is mainly intended for randomization of bioequivalence studies but may be used also for other clinical crossover studies. Contains two helper functions sequences() and williams() to get the sequences of commonly used designs in BE studies.

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Version

Install

install.packages('randomizeBE')

Monthly Downloads

230

Version

0.3-5

License

GPL (>= 2.0)

Maintainer

D. Labes

Last Published

August 24th, 2019

Functions in randomizeBE (0.3-5)

randomizeBE-package

Create a randomisation list for cross-over studies.
williams

Construct sequences of a Williams design
runs.pvalue

2-sided p-value of the runs test
pruns.exact

Exact cumulative distribution function of runs test
RL4

(Block) randomization of subjects, patients into sequence groups
print.rl4

S3 method print for class "rl4"
sequences

Obtain sequences for BE study designs