randomizeBE v0.3-5


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Create a Random List for Crossover Studies

Contains a function to randomize subjects, patients in groups of sequences (treatment sequences). If a blocksize is given, the randomization will be done within blocks. The randomization may be controlled by a Wald-Wolfowitz runs test. Functions to obtain the p-value of that test are included. The package is mainly intended for randomization of bioequivalence studies but may be used also for other clinical crossover studies. Contains two helper functions sequences() and williams() to get the sequences of commonly used designs in BE studies.

Functions in randomizeBE

Name Description
randomizeBE-package Create a randomisation list for cross-over studies.
williams Construct sequences of a Williams design
runs.pvalue 2-sided p-value of the runs test
pruns.exact Exact cumulative distribution function of runs test
RL4 (Block) randomization of subjects, patients into sequence groups
print.rl4 S3 method print for class "rl4"
sequences Obtain sequences for BE study designs
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Type Package
Date 2019-08-24
License GPL (>= 2.0)
NeedsCompilation no
Packaged 2019-08-24 14:22:21 UTC; Detlew
Repository CRAN
Date/Publication 2019-08-24 16:20:08 UTC
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Contributors D. Labes

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