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repfdr (version 1.0)

Replicability Analysis for Multiple Studies of High Dimension

Description

Estimation of Bayes and local Bayes false discovery rates for replicability analysis.

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Version

Install

install.packages('repfdr')

Monthly Downloads

526

Version

1.0

License

GPL (>= 2)

Maintainer

Ruth Heller

Last Published

January 8th, 2014

Functions in repfdr (1.0)

zmat

Three GWAS studies
hconfigs

Enumeration of all possible vectors of association status.
simzmat

Simulated data set
ztobins

Binning of z-scores and estimation of the probabilities in each bin for the null and non-null states.
piem

Estimation of the prior probabilities for each association status vector.
em.control

Control Parameters for the EM algorithm
repfdr

Bayes and local Bayes false discovery rate estimation for replicability analysis
ldr

Estimation of posterior probabilities for the vectors of association status