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rvHPDT (version 3.0)

Calling haplotype-based and variant-based pedigree disequilibrium test for rare variants in pedigrees.

Description

To detecting rare variants for binary traits using general pedigrees, the pedigree disequilibrium tests are proposed by collapsing rare haplotypes/variants with/without weights. To run the test, MERLIN is needed in Linux for haplotyping.

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Version

Install

install.packages('rvHPDT')

Monthly Downloads

184

Version

3.0

License

GPL (>= 2)

Maintainer

Wei Guo

Last Published

May 14th, 2014

Functions in rvHPDT (3.0)

rchild

Internal function.
rvPDT.test.sub

Internal function.
rvPDT.test.permu

Variants-based pedigree disequilibrium test for rare variants in pedigrees.
mypaste

Internal function.
randomPDT

Internal function.
rvPDT.test

Variants-based pedigree disequilibrium test for rare variants in pedigrees.
HapMendlianCheck

Internal function.
mydaoshu

Internal function.
whap.prehap

Prepare haplotype pairs for hPDT tests in pedigree data.
convert.factors.to.strings.in.dataframe

Convert data.frame columns from factors to characters
fullPedigree

Internal function.
rhapPDT

Calling haplotype-based and variant-based pedigree disequilibrium test for rare variants in pedigrees.