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scoper (version 1.3.0)

scoper-package: scoper: Spectral Clustering-Based Method for Identifying B Cell Clones

Description

Provides a computational framework for identification of B cell clones from Adaptive Immune Receptor Repertoire sequencing (AIRR-Seq) data. Three main functions are included (identicalClones, hierarchicalClones, and spectralClones) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) tools:::Rd_expr_doi(" 10.1093/bioinformatics/bty235"). Nouri N and Kleinstein SH (2019) tools:::Rd_expr_doi(" 10.1101/788620"). Gupta NT, et al. (2017) tools:::Rd_expr_doi(" 10.4049/jimmunol.1601850").

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Author

Maintainer: Susanna Marquez susanna.marquez@yale.edu [contributor]

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