SpADEGenes

<p></p><p>The example data provided in our package are transcriptomic profiles of MD-DCs from 9 patients with AS and 10 healthy controls. DE gene statistics group 75 genes identified by LIMMA. Samples description is also provided.
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datasets

internal

A toolbox for a construction of protein-protein interaction networks through the 'STRING' application programming interface, and an inference of Gaussian networks through 'SIMoNe' and 'WGCNA' approach, from DE genes analysis results and expression data. Additional functions are provided to import automatically networks into an active 'Cytoscape' session.

Emmanuel Chaplais

stringgaussnet

PPI and Gaussian Network Construction from Transcriptomic
Analysis Results Integrating a Multilevel Factor

SpADEGenes function

A data frame with 75 observations on the following 5 variables.
  <dl>
    <dt><code>GeneSymbol</code></dt><dd>HGNC gene symbol</dd> <dt><code>EnsemblId</code></dt><dd>Gene Ensembl ID</dd> <dt><code>P.Value</code></dt><dd>Given by LIMMA</dd> <dt><code>Fold.Change</code></dt><dd>Given by LIMMA</dd> <dt><code>logFC</code></dt><dd>log2(Fold.Change)</dd> </dl> 

Format

 Talpin, A. et al. Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression. Arthritis Res. Ther. 16, 417 (2014).

SpADEGenes:
75 DE genes analysis results from LIMMA.

Description

Usage

Arguments

Format

Source

Details

Examples