survmixer (version 1.3)

survmixture_f: Mixture survival function

Description

The function `survmixture_f` computes the survival distribution as a mixture of responders and non-responders. The responders and non-responders distributions are assumed to be Weibull distributions.

Usage

survmixture_f(t, ascale_r, ascale_nr, bshape = 1, p)

Arguments

t

time at which the survival distribution is evaluated

ascale_r

scale parameter for the Weibull distribution for responders

ascale_nr

scale parameter for the Weibull distribution for non-responders

bshape

shape parameter for the Weibull distribution

p

event rate for the response

Value

This function returns the survival function evaluated at t based on a mixture model of responders and non-responders.

References

Design of phase III trials with long-term survival outcomes based on short-term binary results. Marta Bofill Roig, Yu Shen, Guadalupe Gomez Melis. arXiv:2008.12887

Examples

# NOT RUN {
survmixture_f(t=0.2,ascale_r=8,ascale_nr=5.6,p=0.2)
# }