FittingSingleDrug: Fitting single drug dose-response curve
Description
A function to fit single drug dose-response curve with observed response data
Usage
FittingSingleDrug(response.mat, fixed = c(NA, NA, NA, NA))
Arguments
response.mat
a matrix with first column as the drug concentrations and second column as the observed responses
fixed
a parameter to specify which parameters are fixed and at what value they are fixed. NAs for parameter
that are not fixed.
Value
Fitted responses and fitted models are returned.
Details
Single drug dose-response curve is fitted with a commonly used 4-paramter log-losistic (4PL) function.
References
Seber, G. A. F. and Wild, C. J (1989) Nonlinear Regression, New York: Wiley \& Sons (p. 330).