Learn R Programming

synergyfinder (version 0.1)

HSA: HSA synergy score based on highest single agent (HSA) model

Description

A function to calculate HSA synergy score based on HSA model

Usage

HSA(response.mat, correction = TRUE)

Arguments

response.mat
a dose-response matrix with concentrations as row names and column names
correction
a parameter to specify if baseline correction is used or not. Defaults to TRUE.

Value

A matrix of HSA synergy scores for all the dose pairs for a drug combination. For a does pair with at least one zero concentration, 0 is used as the synergy score.