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tidyestimate

The ESTIMATE package has been fundamental for inferring tumor purity from expression data, but its documentation is lacking, and its functions sometimes overstep their bounds while not doing enough. This package is a refresh of ESTIMATE with the goal of maintaining the excellent backbone of the package while increasing its documentation and function scope.

Installation

You can install the released version of tidyestimate from CRAN with:

install.packages("tidyestimate")

And the development version from GitHub with:

# install.packages("devtools")
devtools::install_github("KaiAragaki/tidy_estimate")

Features

tidyestimateESTIMATE
inputdata.frametibblematrix.GCT file
outputdata.frame.GCT file
%>%/`\>`?✔️✖️
size<1MB~7MB

Additionally:

⚡ Faster. tidyestimate doesn’t do any file conversion.

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Version

Install

install.packages('tidyestimate')

Monthly Downloads

289

Version

1.1.1

License

GPL (>= 2)

Issues

Pull Requests

Stars

Forks

Maintainer

Kai Aragaki

Last Published

August 21st, 2023

Functions in tidyestimate (1.1.1)

tidyestimate

tidyestimate: A modern implementation of the ESTIMATE algorithm
common_genes

Genes shared between six expression platforms
purity_data_affy

Affymetrix data used to train ESTIMATE algorithm
ov

Ovarian cancer tumor RNA expression
estimate_score

Infer tumor purity using the ESTIMATE algorithm
filter_common_genes

Remove non-common genes from data frame
gene_sets

Gene sets to infer tumor stromal and immune infiltration
plot_purity

Plot Affymetrix purity scores against ESTIMATE study purity scores