trioGxE v0.1-1
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A data smoothing approach to explore and test gene-environment interaction in case-parent trio data
The package contains functions that 1) estimates
gene-environment interaction between a SNP and a continuous
non-genetic attribute by fitting a generalized additive model
to case-parent trio data, 2) produces graphical displays of
estimated interaction, 3) performs permutation test of
gene-environment interaction; 4) simulates informative
case-parent trios.
Functions in trioGxE
Name | Description | |
hypoTrioDat | Simulated data for a hypothetical example | |
test.trioGxE | Test of gene-environment interaction between a SNP and a continuous non-genetic covariate from case-parent trio data. | |
trioSim | Simulate informative case-parent trios | |
trioGxE | Generalized additive model estimation of gene-environment interaction using data from case-parent trios | |
plot.trioGxE | Graphical display of gene-environment interaction between a SNP and a continuous non-genetic attribute in case-parent trio data | |
pirls.trio-internal | Internal pirls.trio Functions | |
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Details
Type | Package |
Date | 2013-04-02 |
LazyData | true |
License | GPL-2 |
Packaged | 2013-04-02 20:03:19 UTC; jshinb |
NeedsCompilation | no |
Repository | CRAN |
Date/Publication | 2013-04-03 01:39:24 |
depends | gtools , mgcv , msm |
Contributors | Ji-Hyung Shin, Brad McNeney, Jinko Graham |
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[](http://www.rdocumentation.org/packages/trioGxE)