trioGxE v0.1-1
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A data smoothing approach to explore and test gene-environment interaction in case-parent trio data
The package contains functions that 1) estimates
gene-environment interaction between a SNP and a continuous
non-genetic attribute by fitting a generalized additive model
to case-parent trio data, 2) produces graphical displays of
estimated interaction, 3) performs permutation test of
gene-environment interaction; 4) simulates informative
case-parent trios.
Functions in trioGxE
| Name | Description | |
| hypoTrioDat | Simulated data for a hypothetical example | |
| test.trioGxE | Test of gene-environment interaction between a SNP and a continuous non-genetic covariate from case-parent trio data. | |
| trioSim | Simulate informative case-parent trios | |
| trioGxE | Generalized additive model estimation of gene-environment interaction using data from case-parent trios | |
| plot.trioGxE | Graphical display of gene-environment interaction between a SNP and a continuous non-genetic attribute in case-parent trio data | |
| pirls.trio-internal | Internal pirls.trio Functions | |
| No Results! | ||
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Details
| Type | Package |
| Date | 2013-04-02 |
| LazyData | true |
| License | GPL-2 |
| Packaged | 2013-04-02 20:03:19 UTC; jshinb |
| NeedsCompilation | no |
| Repository | CRAN |
| Date/Publication | 2013-04-03 01:39:24 |
| depends | gtools , mgcv , msm |
| Contributors | Ji-Hyung Shin, Brad McNeney, Jinko Graham |
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[](http://www.rdocumentation.org/packages/trioGxE)