hypoTrioDat


A simulated data set with 1000 informative case-parent trios to illustrate the <code>trioGxE</code> package.


dataset

The package contains functions that 1) estimates
gene-environment interaction between a SNP and a continuous
non-genetic attribute by fitting a generalized additive model
to case-parent trio data, 2) produces graphical displays of
estimated interaction, 3) performs permutation test of
gene-environment interaction; 4) simulates informative
case-parent trios.

Ji-Hyung Shin

trioGxE

A data smoothing approach to explore and test gene-environment
interaction in case-parent trio data

hypoTrioDat function

data frame with columns:
<table><tr><td>
     </td>
<td>  column name </td>
<td> type </td>
</tr><tr><td> details </td>
<td>
[,1] </td>
<td> parent 1 </td>
</tr><tr><td> numeric </td>
<td> copy number of the putative risk allele carried by the first parent (0, 1, 2) </td>
<td>
[,2] </td>
</tr><tr><td> parent 2 </td>
<td> numeric </td>
<td> copy number of the putative risk allele carried by the other parent (0, 1, 2) </td>
</tr><tr><td>
[,3] </td>
<td> child </td>
<td> numeric </td>
</tr><tr><td> copy number of the putative allele carried by the child (0, 1, 2) </td>
<td>
[,4] </td>
<td> subpop </td>
</tr><tr><td> numeric </td>
<td> membership for two subpopulations 0, 1 </td>
<td>
     </td>
</tr></table>

hypoTrioDat: Simulated data for a hypothetical example

Description

Usage

Arguments

Format

See Also

	column name	type
details	[,1]	parent 1
numeric	copy number of the putative risk allele carried by the first parent (0, 1, 2)	[,2]
parent 2	numeric	copy number of the putative risk allele carried by the other parent (0, 1, 2)
[,3]	child	numeric
copy number of the putative allele carried by the child (0, 1, 2)	[,4]	subpop
numeric	membership for two subpopulations 0, 1