Parameters that are shared by multiple functions
Observed data matrix with \(l\) rows and 4 columns. Row \(k\) in the matrix represents the observed data from dose level \(k\). The columns are
column 1: number of patient with no DLT, no immune response
column 2: number of patient with no DLT, immune response
column 3: number of patient with DLT, no immune response
column 4: number of patient with DLT, immune response
Option of the probability models:
NONPARA+: non-parametric model
PARA: partially parametric model
PARA+: partially parametric+ model
Default value is NONPARA. See visit for details.
A class VTPRIOR object created by
vtPriorPar for PARA and PARA+ model.
Vector of length 2 representing \((p_L, p_U)\). \(p_L\): lower bound of DLT risk, below which the current dose is considered absolutely safe; \(p_U\): upper bound of DLT risk above which the current dose is considered too toxic
Response rate from the next lower dose level, say, \(l-1\). This can be a scalar representing the mean of the response rate \(E(q^{(l-1)})\), or a vector of posterior samples of the response rate \(q^{(l-1)}\). For \(l=1\), this value is set to \(0\).
Thresholds \(C_1,C_2,C_3\). If the vector length is shorter
than \(3\), it is repeated to have \(3\) elements. See
visit for details.
Digits for print
Random seed
Reserved parameters