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Rdata: Simulation data for Genetic association models for X-chromosome SNPS

Description

A simulated dataset containing 400 observations. The variables list as follows:

Usage

data(Rdata)

Arguments

Format

A data frame with 400 rows and 17 variables.

Details

  • ID. Identification number.

  • OS. Survival indicator, 1 for death, 0 for censoring.

  • OS_time. Duration time of survival.

  • gender. Binary value 0,1 with P(x=1)=0.5 and hazard ratio is 1.

  • Age. Uniform distribution in [20,80] and hazard ratio is 1.02.

  • Smoking. Binary value 0,1 with P(x=1)=0.3 and hazard ratio is 1.2.

  • Treatment. Binary value 0,1 with P(X=1)=0.3 and hazard ratio is 1.2.

  • snp_1. True type in coxph model is 'XCI', minor allele frequency is 0.2, hazard ratio is 1.5.

  • snp_2. True type in coxph model is 'XCI-E', minor allele frequency is 0.3, hazard ratio is 1.5.

  • snp_3. True type in coxph model is 'XCI-S', minor allele frequency is 0.4, hazard ratio is 1.5.

  • snp_4. True type in coxph model is 'XCI', minor allele frequency is 0.3, hazard ratio is 1.

  • snp_5. True type in coxph model is 'XCI-E', minor allele frequency is 0.1, hazard ratio is 1.

  • snp_6. True type in coxph model is 'XCI', minor allele frequency is 0.2, hazard ratio is 1.

  • snp_7. True type in coxph model is 'XCI', minor allele frequency is 0.15, hazard ratio is 1.

  • snp_8. True type in coxph model is 'XCI-E', minor allele frequency is 0.1, hazard ratio is 1.

  • snp_9. True type in coxph model is 'XCI', minor allele frequency is 0.2, hazard ratio is 1.

  • snp_10. True type in coxph model is 'XCI', minor allele frequency is 0.15, hazard ratio is 1.