dd.meddra

<p>This example data uses the HTML level terms of MedDRA
to define AE groups. AE groups may overlap slightly.</p>

datasets

The method zGPS.AO (Zero Inflated Gamma Poisson Shrinker with AE
(Adverse Event) ontology) is based on the zero-inflated negative binomial
distribution.
It estimates the association between a specific vaccine and an adverse event
group, as well as associations between that vaccine and individual adverse
events within the adverse event group. This model handles the adverse event
count data with excess zeros and over-dispersion, and it allows borrowing
information from adverse event data in the same group. Details can be found
in  "Data Mining in Large Frequency Tables With Ontology, with an Application
to the Vaccine Adverse Event Reporting System."
Bangyao Zhao, Lili Zhao (2020) <arXiv:2010.12471>.

Bangyao Zhao

zGPS.AO

Zero Inflated Gamma Poisson Shrinker with Adverse Event Ontology

Lili Zhao

Michael Kleinsasser

dd.meddra function

<p>An object of class <code>data.frame</code> with 12482 rows and 2 columns.</p>

dd.meddra: Medical Dictionary for Regulatory Activities (MedDRA)

Description

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Details