Chromosome Instability Index
Description
The CINdex package addresses important area of high-throughput
genomic analysis. It allows the automated processing and analysis of the
experimental DNA copy number data generated by Affymetrix SNP 6.0 arrays or
similar high throughput technologies. It calculates the chromosome instability
(CIN) index that allows to quantitatively characterize genome-wide DNA copy
number alterations as a measure of chromosomal instability. This package
calculates not only overall genomic instability, but also instability in terms
of copy number gains and losses separately at the chromosome and cytoband level.