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GOSemSim

Implemented five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for estimating GO semantic similarities. Support many species, including Anopheles, Arabidopsis, Bovine, Canine, Chicken, Chimp, Coelicolor, E coli strain K12 and Sakai, Fly, Human, Malaria, Mouse, Pig, Rhesus, Rat, Worm, Xenopus, Yeast, and Zebrafish.

Authors

Guangchuang YU, School of Public Health, The University of Hong Kong http://guangchuangyu.github.io

Citation

Please cite the following article when using GOSemSim:

Yu G, Li F, Qin Y, Bo X, Wu Y and Wang S. 
GOSemSim: an R package for measuring semantic similarity among GO terms and gene products.
Bioinformatics, 2010, 26(7):976-978. 

URL: http://bioinformatics.oxfordjournals.org/content/26/7/976.full

License

All source code is copyright, under the Artistic-2.0 License. For more information on Artistic-2.0 License see http://opensource.org/licenses/Artistic-2.0

Installation

To install:

  • the latest released version: biocLite("GOSemSim")
  • the latest development version: devtools::install_github("GuangchuangYu/GOSemSim")

Find out more at http://www.bioconductor.org/packages/release/bioc/html/GOSemSim.html and check out the vignette.

Documentation

To view the vignette of GOSemSim installed in your system, start R and enter:

vignette("GOSemSim", package="GOSemSim")

More documents can be found in http://www.bioconductor.org/packages/clusterProfiler, http://www.bioconductor.org/packages/DOSE and http://guangchuangyu.github.io/tags/gosemsim.

Bugs/Feature requests

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Version

Version

1.30.2

License

Artistic-2.0

Maintainer

Guangchuang Yu

Last Published

February 15th, 2017

Functions in GOSemSim (1.30.2)

GOSemSim-package

Gene Ontology-based Sematic Similarity Measures
clusterSim

Semantic Similarity Between Two Gene Clusters
IC

Information content of GO terms
infoContentMethod

information content based methods
goSim

Semantic Similarity Between Two GO Terms
loadGOMap

loadGOMap
termSim

termSim
mclusterSim

Pairwise Semantic Similarities for a List of Gene Clusters
combineScores

combining similarity matrix to similarity score
getDb

getDb
loadICdata

Load IC data
wangMethod

wangMethod
geneSim

Semantic Similarity Between two Genes
mgeneSim

Pairwise Semantic Similarity for a List of Genes
getSupported_Org

getSupported_Org
mgoSim

Semantic Similarity Between two GO terms lists