Efficient Score Statistics for Genome-Wide SNP Set Analysis
Description
An implementation of the use of efficient score statistics
in genome-wide SNP set analysis with complex traits. Three standard score statistics
(Cox, binomial, and Gaussian) are provided, but the package is easily extensible to
include others. Code implementing the inferential procedure is primarily written in C++ and
utilizes parallelization of the analysis to reduce runtime. A supporting function offers
simple computation of observed, permutation, and FWER and FDR adjusted p-values.