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RadioGx

RadioGx and PharmacoGx: Integrated prediction tools for combining radiotherapy with systemic agents

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Version

Install

install.packages('RadioGx')

Monthly Downloads

8

Version

0.0.2

License

GPL-3

Maintainer

Benjamin HaibeKains

Last Published

December 19th, 2019

Functions in RadioGx (0.0.2)

plotCurve

Plot radiation dose-response curve
radSensitivitySig

Creates a signature representing the association between gene expression (or other molecular profile) and radiation dose response, for use in radiation sensitivity analysis.
linearQuadraticModel

Fit linear-quadratic curves to dose-response data
summarizeSensitivityProfiles

Takes the sensitivity data from a RadioSet, and summarises them into a drug vs cell line table
radiationInfo<-

radiationInfo<- Generic
subsetTo

A function to subset a RadioSet to data containing only specified radiations, cells and genes
radiationInfo

radiationInfo Generic
mDataNames,RadioSet-method

mDataNames
RadioSet-class

A Class to Contain RadioGenomic datasets together with their curations
show,RadioSet-method

Show a RadioSet
summarizeMolecularProfiles

Takes molecular data from a PharmacoSet, and summarises them into one entry per drug
radiationTypes<-

radiationTypes<- Generic
show,RadioSig-method

Show RadioGx Signatures
showSigAnnot

Show the Annotations of a signature object
[,RadioSet,ANY,ANY,ANY-method

`[`
radiationTypes

radiationTypes Generic
computeD10

Compute D10
checkRSetStructure

A function to verify the structure of a RadioSet
dim,RadioSet-method

Get the dimensions of a RadioSet
Cleveland_small

Cleaveland_mut RadioSet subsetted
.linearQuadratic

Linear quadratic
computeSF2

Compute SF2
doseResponseCurve

Plot drug response curve of a given drug and a given cell for a list of rSets (objects of the RadioSet class).
RadioSet

RadioSet constructor
computeAUC

computeAUC: computes AUC