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SMASH (version 1.0.0)

Subclone Multiplicity Allocation and Somatic Heterogeneity

Description

Cluster user-supplied somatic read counts with corresponding allele-specific copy number and tumor purity to infer feasible underlying intra-tumor heterogeneity in terms of number of subclones, multiplicity, and allocation (Little et al. (2019) ).

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Version

Install

install.packages('SMASH')

Monthly Downloads

144

Version

1.0.0

License

GPL (>= 3)

Maintainer

Paul Little

Last Published

February 27th, 2025

Functions in SMASH (1.0.0)

ITH_optim

ITH_optim
gen_ITH_RD

gen_ITH_RD
eS

A collection of pre-defined subclone configurations.
vis_GRID

vis_GRID
gen_subj_truth

gen_subj_truth
grid_ITH_optim

grid_ITH_optim