Learn R Programming

⚠️There's a newer version (1.1.0) of this package.Take me there.

beadarrayMSV (version 1.0.3)

Analysis of Illumina BeadArray SNP data including MSV markers

Description

Imports bead-summary data from Illumina scanner. Pre-processes using a suite of optional normalizations and transformations. Clusters and automatically calls genotypes, critically able to handle markers in duplicated regions of the genome (multisite variants; MSVs). Interactive clustering if needed. MSVs with variation in both paralogs may be resolved and mapped to their respective chromosomes. Quality control including pedigree checking and visual assessment of clusters. Too large data-sets are handled by working on smaller subsets of the data in sequence.

Copy Link

Version

Install

install.packages('beadarrayMSV')

Monthly Downloads

19

Version

1.0.3

License

GPL (>= 2)

Maintainer

Lars Gidskehaug

Last Published

December 13th, 2010

Functions in beadarrayMSV (1.0.3)

findClusters

Suggest clusters based on histograms
findSeTheta

Scale pooled standard errors after polar transformation
callGenotypes

Clustering and calling of genotypes
BeadSetIllumina-class

Class to Contain Objects Describing High-Throughput Illumina BeadArrays
cart2pol

Transformation from Cartesian to polar coordinates
manualCall

Interactive calling of genotype for single marker
getCenters

Estimate starting points for clustering
locateParalogues

Match paralogs with chromosomes
unmixParalogues

Partially resolve the paralogs of MSV-5s
preprocessBeadSet

Pre-processing of BeadSetIllumina objects
getNormInd

Retrieve sub-bead pool indexes
createAlleleSet

Create AlleleSetIllumina or MultiSet objects
normalizeShearedChannels

Channel normalization
translateTheta

Convert genotype calls to allele information
makeDiploidCalls

Constrain calls to diploid representation
getSingleCalls

Identify MSV-5 paralogs with equal genotypes
AlleleSetIllumina-class

Class to Contain Objects Describing High-Throughput Illumina BeadArrays
BSRed.193

Atlantic salmon genotype data with mainly MSV-5 markers
scatterArrays

Cartesian scatter-plots of two-colour intensities
validateCallsPedigree

Pedigree validation of genotypes
generatePolyCenters

Generate list of possible genotype categories
writeAlleleSet

Write AlleleSetIllumina data to files
makeFilenames

Generate filenames reflecting normalizations
shearRawSignal

Affine transformation of axes
findPolyploidClusters

K-means clustering
transformChannels

Signal transformation
readBeadSummaryOutput

Read bead-summary intensities from two colour Illumina (Infinium) scanner
countFailedSNP

Calculate ratio of called markers for each array
assignParalogues

Assign MSV-5 paralogs to chromosomes
getNoiseDistributions

Estimate median and robust spread of background noise
beadarrayMSV-package

beadarrayMSV: Package for analysis of high-throughput Illumina BeadArrays
resolveInheritanceSNP

Track parental alleles in offspring
plotGenotypes

Plotting of genotyped markers
testHardyWeinberg

Test for Hardy-Weinberg equilibrium