Learn R Programming

cosmiq (version 1.6.0)

cosmiq - COmbining Single Masses Into Quantities

Description

cosmiq is a tool for the preprocessing of liquid- or gas - chromatography mass spectrometry (LCMS/GCMS) data with a focus on metabolomics or lipidomics applications. To improve the detection of low abundant signals, cosmiq generates master maps of the mZ/RT space from all acquired runs before a peak detection algorithm is applied. The result is a more robust identification and quantification of low-intensity MS signals compared to conventional approaches where peak picking is performed in each LCMS/GCMS file separately. The cosmiq package builds on the xcmsSet object structure and can be therefore integrated well with the package xcms as an alternative preprocessing step.

Copy Link

Version

Version

1.6.0

License

GPL-3

Maintainer

David Fischer

Last Published

February 15th, 2017

Functions in cosmiq (1.6.0)

retention_time

Detection of chromatographic peak locations from extracted ion chromatograms (EICs)
eicmatrix

Generate matrix of combined extraced ion chromatograms (EICs)
create_datamatrix

Quantifying mz/RT intensities using peak locations from master map
peakdetection

An algorithm for the detection of peak locations and boundaries in mass spectra or ion chromatograms
cosmiq

cosmiq - main wrapper function
combine_spectra

Combine mass spectra of each scan and each file into a single master spectrum
quantify_combined

Generate report with combined ion intensities