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drc (version 2.3-96)

Analysis of dose-response curve data

Description

Analysis of dose-response curves in biology, environmental sciences, medicine, pharmacology, toxicology

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Install

install.packages('drc')

Monthly Downloads

28,339

Version

2.3-96

License

GPL-2 | file LICENCE

Maintainer

Christian Ritz

Last Published

November 29th, 2013

Functions in drc (2.3-96)

chickweed

Germination of common chickweed (Stellaria media)
CRS.5a

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
EXD

Exponential decay model
LL.2

The two-parameter log-logistic function
G.aparine

Herbicide applied to Galium aparine
M.bahia

Effect of an effluent on the growth of mysid shrimp
P.promelas

Effect of sodium pentachlorophenate on growth of fathead minnow
anova.drc

ANOVA for dose-response model fits
acidiq

Acifluorfen and diquat tested on Lemna minor.
gaussian

Normal and log-normal biphasic dose-response models
logistic

The logistic model
RScompetition

Competition between two biotypes
S.alba

Potency of two herbicides
lepidium

Dose-response profile of degradation of agrochemical using lepidium
CRS.4a

The Cedergreen-Ritz-Streibig model
gompertz

Mean function for the Gompertz dose-response or growth curve
mecter

Mechlorprop and terbythylazine tested on Lemna minor
maED

Estimation of ED values using model-averaging
isobole

Creating isobolograms
algae

Volume of algae as function of increasing concentrations of a herbicide
ryegrass

Effect of ferulic acid on growth of ryegrass
llogistic

The log-logistic function
lnormal

Log-normal dose-response model
spinach

Inhibition of photosynthesis
methionine

Weight gain for different methionine sources
LL.4

The four-parameter log-logistic function
BC.5

The Brain-Cousens hormesis models
backfit

Calculation of backfit values from a fitted dose-response model
daphnids

Daphnia test
AR

Asymptotic regression model
H.virescens

Mortality of tobacco budworms
LL.5

The five-parameter log-logistic function
NEC

Dose-response model for estimation of no effect concentration (NEC).
diagnostics

Information on estimation
getInitial

Showing starting values used
PR

Expected or predicted response
MAX

Maximum mean response
coef.drc

Extract Model Coefficients
W1.4

The four-parameter Weibull functions
mr.test

Mizon-Richard test for dose-response models
W1.2

The two-parameter Weibull functions
S.capricornutum

Effect of cadmium on growth of green alga
etmotc

Effect of erythromycin on mixed sewage microorganisms
earthworms

Earthworm toxicity test
boxcox.drc

Transform-both-sides Box-Cox transformation
braincousens

The Brain-Cousens hormesis models
heartrate

Heart rate baroreflexes for rabbits
SI

Comparing selectivity indices across curves
baro5

The modified baro5 function
compParm

Comparison of parameters
logLik.drc

Extracting the log likelihood
deguelin

Deguelin applied to chrysanthemum aphis
drmc

Sets control arguments
print.summary.drc

Printing summary of non-linear model fits
lin.test

Lack-of-fit test for the mean structure based on cumulated residuals
fitted.drc

Extract fitted values from model
mselect

Dose-response model selection
confint.drc

Confidence Intervals for model parameters
gompertzd

The derivative of the Gompertz function
mixture

Fitting binary mixture models
neill.test

Neill's lack-of-fit test for dose-response models
twophase

Two-phase dose-response model
weibull1

Weibull model functions
lettuce

Hormesis in lettuce plants
ursa

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
predict.drc

Prediction
modelFit

Assessing the model fit
residuals.drc

Extracting residuals from the fitted dose-response model
vinclozolin

Vinclozolin from AR in vitro assay
terbuthylazin

The effect of terbuthylazin on growth rate
cedergreen

The Cedergreen-Ritz-Streibig model
mrdrm

Model-robust dose-response modelling
getMeanFunctions

Display available dose-response models
summary.drc

Summarising non-linear model fits
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
rdrm

Simulating a dose-response curve
simDR

Simulating ED values under various scenarios
yieldLoss

Calculating yield loss parameters
vcov.drc

Calculating variance-covariance matrix for objects of class 'drc'
plot.drc

Plotting fitted curves for a 'drc' or 'mrdrc' object
secalonic

Root length measurements
noEffect

Testing if there is a dose effect at all
leaflength

Leaf length of barley
W1.3

The three-parameter Weibull functions
beetGrowth

Example of plant growth curve from Covarelli and Onofri (1998)
MM

Michaelis-Menten model
ED.drc

Estimating effective doses
O.mykiss

Test data from a 21 day fish test
LL.3

The three-parameter log-logistic function
comped

Comparison of effective dose values
auxins

Effect of technical grade and commercially formulated auxin herbicides
drm

Fitting dose-response models
bread.drc

Bread and meat for the sandwich
fplogistic

Fractional polynomial-logistic dose-response models
gompGrowth

Gompertz growth models
glymet

Glyphosate and metsulfuron-methyl tested on algae.
finney71

Example from Finney (1971)
hatvalues.drc

Model diagnostics for nonlinear dose-response models
germination

Germination of three crops
selenium

Data from toxicology experiments with selenium
update.drc

Updating and re-fitting a model
searchdrc

Searching through a range of initial parameter values to obtain convergence
print.drc

Printing key features