Permutation Randomization
Description
Provides randomization using permutation for applications. To provide a Quality Control (QC) check, QC samples can be randomized within strata. A second function allows for the ability to ”switch” samples to meet set requirements and perform a certain amount of minimization on these switches. The functions are flexible for users by specifying strata size and number of QC samples per strata. The randomization meets the following requirements
• QC sample requirements: QC samples not adjacent, QC
samples from same mother must follow certain patterns.
• Matched sample sets must be within a single strata, and next
to each other.