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qpNCA

Overview

qpNCA is qPharmetra’s R package for Noncompartmental Analysis. It provides regulatory-quality calculations of NCA parameters, using code routinely tested against independently-validated output. You can find appropriate manuals in the vignettes directory, and you can find tests and reference data in the tests directory.

Installation

The easiest way to get qpNCA is to install from CRAN:

install.packages("qpNCA")

Alternatively, install from github:

devtools::install_github('qpharmetra/qpNCA')

You can use the issues feature on github to report issues.

Usage

A good place to start is the help for qpNCA().

library(qpNCA)
?qpNCA
example(qpNCA)

Or see the vignettes, like this one for example.

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Version

Install

install.packages('qpNCA')

Monthly Downloads

238

Version

1.1.6

License

GPL-3

Maintainer

Jan Huisman

Last Published

August 16th, 2021

Functions in qpNCA (1.1.6)

filenamefun

Create File Name for Regression Plots
tab.corr

Tabulate Corrections
qpNCA

Perform Non-compartmental Analysis
calc.par

Calculate NCA Parameters
trapm

Calculate Area Under the Moment Curve Using Trapezoids
calc.ctmax

Calculate Cmax and Tmax
plot_reg

Plot Regression Curves
correct.loq

Impute Concentrations Below the Limit of Quantitation
correct.conc

Correct Missing Concentration
lag_lead

Estimate Lagging and Leading Times and Concentrations
correct.time

Correct Concentrations for Time Deviations
est.thalf

Calculate Lambda_z and Elimination Half-life
calc.par.th

Calculate Lambda_z Parameters
check.input

Check qpNCA function arguments for validity
trap

Calculate Area Under the Curve Using Trapezoids
titlefun

Create Title for Regression Plots
interpol

Interpolate Concentrations