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rescue (version 1.0.3)

Bootstrap Imputation for Single-Cell RNA-Seq Data

Description

Given a log-transformed expression matrix and list of informative genes: subsample informative genes, cluster samples using shared nearest neighbors clustering, estimate missing expression values with the distribution mean of means extrapolated from these cell clusterings, and return an imputed expression matrix. See Tracy, S., Yuan, G.C. and Dries, R. (2019) for more details.

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install.packages('rescue')

Monthly Downloads

19

Version

1.0.3

License

GPL-2 | GPL-3

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Maintainer

Sam Tracy

Last Published

July 18th, 2020

Functions in rescue (1.0.3)

computeHVG

Compute Highly Variable Genes
sampleImputation

Sample-mean Estimation
bootstrapImputation

Bootstrap Imputation
clusterLouvain

Cluster Cells via Louvain Algorithm
constructNN

Nearest Network