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tilingArray (version 1.50.0)

Transcript mapping with high-density oligonucleotide tiling arrays

Description

The package provides functionality that can be useful for the analysis of high-density tiling microarray data (such as from Affymetrix genechips) for measuring transcript abundance and architecture. The main functionalities of the package are: 1. the class 'segmentation' for representing partitionings of a linear series of data; 2. the function 'segment' for fitting piecewise constant models using a dynamic programming algorithm that is both fast and exact; 3. the function 'confint' for calculating confidence intervals using the strucchange package; 4. the function 'plotAlongChrom' for generating pretty plots; 5. the function 'normalizeByReference' for probe-sequence dependent response adjustment from a (set of) reference hybridizations.

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Version

Version

1.50.0

License

Artistic-2.0

Maintainer

Zhenyu Xu

Last Published

February 15th, 2017

Functions in tilingArray (1.50.0)

segmentation

The class segmentation represents a segmentation result.
normalizeByReference

Probe-specific normalization of hybridization intensities from an oligonucleotide microarray
readCel2eSet

Read celfiles into an ExpressionSet object.
plotPenLL

Plot the log-likelihood and penalized log-likelihoods (AIC, BIC)
PMindex

Find the index of the exact match (PM) or background probes from a probeAnno environment
plotAlongChrom

Plot signals and segmentation for a region of a chromosome
plotFeatures

Plot genomic features for a region along a chromosome
segChrom

Fit a piecewise constant curve to along chromosome data (wrapper function)
plotSegmentationDots

Plot points for a region along a chromosome
comparisonPlot

Plot a vertical layout of panels for the comparison of different along-chromosome profiles.
qcPlots

Generate simple diagnostic plots for Affymetrix tiling array data
segnf

Example of a segmentation output object
segment

Fit a piecewise constant curve: segmentation by dynamic programming
otherStrand

Return the name of the opposite strand
sampleStep

Sampling of ascending numbers to ensure minimal spacing.
costMatrix

Segmentation cost matrix
breakpointsPretend

Accessor methods for breakpointsPretend objects - not to be called by the user.
gffSub

Example of a genomic feature object
posMin

Find the smallest positive number in a vector
tilingArray-package

tilingArray package overview
plotSegmentationHeatmap

Plot a heatmap diagram for a region along a chromosome
findSegments

Fit a piecewise constant curve to a sequence of numbers -- OBSOLETE, please use function segment instead.
plotAlongChromLegend

Plot a legend for genomic features